Table of Contents
What is a good NTx score?
Male: 21-83. Female (premenopausal): 17-94. Female (postmenopausal): 26-124.
What does a low NTx telopeptide mean?
Interpretation. Provides information to assist in interpretation of the test results. Elevated levels of N-terminal telopeptide (NTx) indicate increased bone resorption. Most patients with osteopenia or osteoporosis have low, but unbalanced, bone turnover, with bone resorption dominating over bone formation.
What is NTx blood test?
The NTx test measures the concentration of cross-linked N-telopeptides of type I collagen. 1. Levels of NTx correlate with the rate of bone resorption. 2,3. Bone resorption rates exceeding bone formation result in a net loss of bone and ultimately osteopenia or osteoporosis.
What does my CTX score mean?
Elevated levels of beta-C-terminal telopeptide (CTx) indicate increased bone resorption. Increased levels are associated with osteoporosis, osteopenia, Paget disease, hyperthyroidism, and hyperparathyroidism.
What is a telopeptide test for?
This test is used to assess the loss of bone mass (bone resorption) in cases of osteoporosis or other bone diseases such as Paget’s disease.
What is the telopeptide test for?
What does N telopeptide measure?
Urinary N-telopeptide has been used for monitoring treatment for osteoporosis for a long time, but now, clinicians are using it to predict the onset of osteoporosis. The new ELISA immunoassay for the urinary excretion of cross-linked collagen peptides is a reliable and specific biochemical marker of bone resorption.
What is a good C telopeptide number?
The reference ranges for C-terminal telopeptide in urine are as follows : Adults: 1.03 ± 0.41 ng/mL. Children: 8.00 ± 3.37 ng/mL.
What is normal range for C telopeptide?
What are the markers for osteoporosis?
Currently, the most sensitive markers of formation in postmenopausal osteoporosis are FAO, OC and PINP, whereas the best resorption markers are urine NTX and serum CTX telopeptides.
What does low bone turnover mean?
Low turnover disease or adynamic bone disease (ABD) is characterized by a low number of osteoblasts with normal or reduced numbers of osteoclasts. Mineralization proceeds at a normal rate, resulting in normal or decreased osteoid thickness.
What is a good CTx score?
Information on the Serum CTX Test
| CTX Value | Risk for ONJ |
|---|---|
| 300 to600 pg/ml (normal) | none |
| 150 to 299 pg/ml | none to minimal |
| 101 to 149 pg/ml | moderate |
| Less than 100 pg/ml | high |
What is the most accurate test for osteoporosis?
It may be done using X-rays, dual-energy X-ray absorptiometry (DEXA or DXA), or a special CT scan that uses computer software to determine bone density of the hip or spine. For various reasons, the DEXA scan is considered the “gold standard” or most accurate test.
What is normal range for C-telopeptide?
What are the clinical indications for performing the N-telopeptide cross-links urine test?
Following are the clinical indications for performing the N-Telopeptide Cross-Links Urine Test: 1 Monitoring the effects of antiresorptive therapy 2 Frequent and/or unusual bone fractures 3 Loss of height 4 Hair loss 5 Brittle nails 6 Fatigue 7 Developmental issues, such as delayed onset of puberty
Is DXA scan a gold standard for urinary N-telopeptide?
The results from DXA scan were taken as gold standard against urinary N-telopeptide. Then the patients were divided into two groups control and study. The control group contains patients who had normal DXA, while study group contains patients having either osteopenia or osteoporosis.
Can urinary N-telopeptide be used as a diagnostic tool for osteoporosis?
Conclusion Urinary N-telopeptide can give reproducible results and be able to assist in the evaluation of the quantity as well as the quality and be a good judge of someone’s risk of fracture. Hence, urinary N-telopeptide can be used as a diagnostic tool for diagnosing osteoporosis.
What is the standard deviation of urinary N-telopeptide?
The standard deviation of urinary N-telopeptide value in case was 159.9. Conclusion Urinary N-telopeptide can give reproducible results and be able to assist in the evaluation of the quantity as well as the quality and be a good judge of someone’s risk of fracture.